183 research outputs found
Interaction effects in assembly of magnetic nanoparticles
A specific absorption rate of a dilute assembly of various random clusters of
iron oxide nanoparticles in alternating magnetic field has been calculated
using Landau- Lifshitz stochastic equation. This approach simultaneously takes
into account both the presence of thermal fluctuations of the nanoparticle
magnetic moments, and magneto-dipole interaction between the nanoparticles of
the clusters. It is shown that for usual 3D clusters the intensity of magneto-
dipole interaction is determined mainly by the cluster packing density eta =
Np*V/Vcl, where Np is the average number of the particles in the cluster, V is
the nanoparticle volume, and Vcl is the cluster volume. The area of the low
frequency hysteresis loop and the assembly specific absorption rate have been
found to be considerably reduced when the packing density of the clusters
increases in the range of 0.005 < eta < 0.4. The dependence of the specific
absorption rate on the mean nanoparticle diameter is retained with increase of
eta, but becomes less pronounced. For fractal clusters of nanoparticles, which
arise in biological media, in addition to considerable reduction of the
absorption rate, the absorption maximum is shifted to smaller particle
diameters. It is found also that the specific absorption rate of fractal
clusters increases appreciably with increase of the thickness of nonmagnetic
shells at the nanoparticle surfaces.Comment: The paper is accepted for Nanoscale Res. Let
Networking in the food sector of regional economy
Purpose: The article aims to study the features and the directions of development of network interaction of subjects of the food sector in different regions of the economy. Design/Methodology/Approach: The use of different methodological approaches allowed us to formulate a holistic management concept for the development of a network of competences in the food sector of the regional economy. Findings: The study identified the subjects of such interaction, as well as features that allow them to unite into groups that form networks of competencies. Considering the food sector of the region's economy as a socio-economic system, noted its extreme structural complexity, which necessitates the development of special approaches to its management, or rather the need for structural management is presented. The format of such interaction is a network of competencies, representing a spatially localized socio-economic structure formed on the initiative of active subjects of the regional economy. Practical Implications: The results obtained can be used as a basis for designing a network form of development of the food sector of the region's economy, taking into account the nature of placement and interaction of participants, as well as allowing for effective use of their resource capabilities, experience and knowledge.
Originality/Value: In order to overcome the problems associated with the formation of network identity, network management competence is proposed to use a structured approach allowing them to make targeted decisions based on objective conditions and institutional nature.peer-reviewe
Innovational methods of development of intellectual labor for economyβs security
The notion βdevelopment of intellectual labor for the purpose of economyβs securityβ is viewed as development of societyβs intellectual potential that includes the protected socio-economic information, developed by a person or a group of persons. The social factors that reduce economic security and their consequences in economy are given, namely: negative dynamics of implementing new progressive technologies into production, insufficient coordination of work in the sphere of innovational development, etc. The forms of intellectual development of human resources (intellectual development of personality, control over intellectual information) are offered, which bring the countryβs economy to competitiveness and security. The traditional and innovational methods of intellectual labor development are studied (studying in universities and colleges, increase of personnelβs qualification in view of academic degrees (Ph.D., doctor of economics), as well as receipt of economic information through Internet resources, scientific publication, statistical information, etc.), as well as the methods of development of IT services and methods of prevention of intellectual diversions and violation of information confidentiality. It is offered to implement the program of equal initial possibilities for intellectual development of human resources in view of access to higher education, creative activities, as well as legal protection for everyone, etc. Analysis of implementation of innovational methods of intellectual labor development supposes planning activities in view of development of intellectual labor for the purpose of the regionβs economyβs security.peer-reviewe
Predictors of Long-Term Outcomes after Surgical Myocardial Revascularization
High mortality from cardiovascular diseases (CVD) requires improved approaches to the treatment of this socially significant pathology. Wide implementation of surgical myocardial revascularization makes it possible to improve significantly both life quality and expectancy in patients with coronary heart disease. The aim of this work was to analyze the literature on the impact of preoperative, operative and postoperative factors on the long-term prognosis after coronary artery bypass grafting (CABG). The review refers to both recent and earlier informative works. The target groups for this article are therapists, cardiologists, rehabilitologists, who work with patients in the short and long term after CABG. Data of Russian and foreign literature show that the long-term prognosis after CABG is largely determined by preoperative factors, in particular β age, set of cardiovascular risk factors (RF) and comorbidity, specifically β severity of coronary and systemic atherosclerosis, incident cardiovascular complications, structural and functional state of the heart. In the aggregate these factors reflect the cumulative effect and further potential of actual cardiovascular RFs, affect longterm risk of adverse events, and determine the therapeutic targets of secondary prevention. Priority of arterial conduits and completeness of revascularization are the main operative factors that determine the course of the long-term period after CABG. Among the postoperative factors, the efficiency of secondary CVD prevention is of paramount importance, in particular β achievement of target RF levels, compensation of cardiac and extracardiac pathology, adherence to the long-term medical therapy, known to improve outcomes based on specific comorbidity. Efficiency of secondary CVD prevention largely depends on patient's health attitudes, the key influence on which beyond attending physician can be provided by participation in rehabilitation programs, teaching patients the meaning and essentials of lifestyle modification and cardiovascular RFsβ control
Analysis of factors associated with arterial stiffness in the general working-age population
Aim. To examine associations of cardio-ankle vascular index (CAVI) with classical, behavioral and social risk factors (RFs) of cardiovascular disease (CVD) in adult population.Material and methods. The study included 1365 people (women, 59%) from a representative sample aged 25-64 years (ESSE-RF), who underwent standard cardiology screening and volume sphygmography (VaSera-1500). All respondents signed an informed consent to participate in the study. The analysis included blocks of classical, social and behavioral risk factors for CVD. A linear model was used to identify associations. An error rate of <5% was considered significant.Results. Age, sex, systolic blood pressure (SBP), triglycerides were associated with higher CAVI values, and body mass index (BMI) was associated with lower values, respectively. After 45 years, a direct association with heart rate (HR) became increasingly important, while after 50 years β with diabetes and the intake of beta-blockers, while the association between diabetes and CAVI was observed only among individuals not taking angiotensin-converting enzyme (ACE) inhibitors. A direct association was found with high-sensitivity C-reactive protein (hsCRP) in men, and an inverse association with diuretics in women, respectively. A sedentary work in combination with a history of bronchitis or with positive family history for CVD showed a direct relationship, while a sufficient physical activity (PA) showed an inverse relationship with the studied indicator, but only among people with belowaverage income.Conclusion. According to the data obtained, in addition to age and sex, the following risk factors made a significant contribution to CAVI parameters in the examined population: BMI, SBP, triglycerides, diabetes, HR, intake of betablockers, diuretics, ACE inhibitors; hsCRP, PA. The unfavorable role of betablockers, high HR, diabetes, sedentary work, chronic lung pathology, hereditary burden, as well as the protective role of ACE inhibitors, diuretics and intense PA in relation to arterial stiffness in the working-age population has been shown. Additional studies are needed to determine the nature of a number of associations. The results obtained may contribute to the study of CAVI role in risk stratification and further development of methodological approaches to CVD prevention
ΠΠ΅ΡΠ΅ΡΠΌΠΈΠ½Π°Π½ΡΡ ΠΊΠΎΠ½ΡΡΠΎΠ»Ρ Π°ΡΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ Π³ΠΈΠΏΠ΅ΡΡΠΎΠ½ΠΈΠΈ Π² Π³ΠΈΠΏΠ΅ΡΡΠ΅Π½Π·ΠΈΠ²Π½ΠΎΠΉ ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΈ, ΠΏΠΎΠ»ΡΡΠ°ΡΡΠ΅ΠΉ ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΡΡ ΡΠ΅ΡΠ°ΠΏΠΈΡ
Highlights. The leading factor of ineffective arterial hypertension (AH) control in the population taking medications was the number of metabolic risk factors (RF). In addition, in men, the odds of reaching the blood pressure targets were lower if there was a history of kidney disease and bronchitis, and higher, if statins and hypotensive drugs were taken together, respectively. In women, heart rate equal or higher than 75 beats/min and total carotid atherosclerotic plaque thickness were associated with lower and a visit to a physician in the past year - with higher odds of effective hypertension control, respectively.Aim. Analysis of factors associated with reaching blood pressure targets in hypertensive population taking medications.Methods. We examined men and women of 25-64 y.o., randomly drawn from general population, having hypertension and receiving medications. All participants underwent standardized cardiac screening, including a survey on a number of socio-demographic, psychosocial, behavioral variables, traditional and metabolic cardiovascular risk factors, life quality. We measured anthropometric and blood pressure variables, "intima-media" thickness, presence and total thickness of carotid atherosclerotic plaques. Analysis included data from 480 respondents. Parametric and nonparametric statistics were used. To analyze relationships, multivariable logistic regression was used. An error probability <5% was considered statistically significant.Results. After adjustment for age, wealth level, cardio-vascular deseases and the number of antihypertensive drugs, the following factors increased the chances of effective treatment for hypertension in men - statins, positive answer to the question βDo you feel pain or discomfort?β on the EQ5D scale. Lower odds for detecting target blood pressure levels were associated to the count of metabolic syndrome components according to IDF criteria except arterial hypertension (0-4), kidney disease, previous bronchitis, age. A direct association with the effectiveness of treatment for hypertension in women was shown by a visit to the doctor during the past year, and the opposite - the number of metabolic syndrome components, heart rate β₯75 per minute and the total thickness of carotid atherosclerotic plaques, respectively.Conclusion. Lack of hypertension control was associated to metabolic risk factors count, age, kidney disease, heart rate β₯75 per minute, previous bronchitis, lack of visit to a doctor over the past year, as well as total thickness of carotid atherosclerotic plaques. The situation can be improved by deliberately losing weight, taking statins by all people at very high and high risk, and seeing a doctor regularly. It is necessary to further study the factors that hinder achievement of blood pressure targets, as well as methods aimed at the prevention and effective correction of metabolic disorders.ΠΡΠ½ΠΎΠ²Π½ΡΠ΅ ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΡ. ΠΠ΅Π΄ΡΡΠΈΠΌ ΡΠ°ΠΊΡΠΎΡΠΎΠΌ Π½Π΅ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΡΡΠΎΠ»Ρ Π°ΡΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ Π³ΠΈΠΏΠ΅ΡΡΠΎΠ½ΠΈΠΈ (ΠΠ) Π² ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΠΎ Π»Π΅ΡΠ°ΡΠ΅ΠΉΡΡ ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΈ Π±ΡΠ»ΠΎ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠΈΡΠΊΠ° (Π€Π ). ΠΡΠΎΠΌΠ΅ ΡΠΎΠ³ΠΎ, Ρ ΠΌΡΠΆΡΠΈΠ½ ΡΠ°Π½ΡΡ Π΄ΠΎΡΡΠΈΠΆΠ΅Π½ΠΈΡ ΡΠ΅Π»Π΅Π²ΠΎΠ³ΠΎ ΡΡΠΎΠ²Π½Ρ Π°ΡΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π΄Π°Π²Π»Π΅Π½ΠΈΡ Π±ΡΠ»ΠΈ Π½ΠΈΠΆΠ΅ ΠΏΡΠΈ Π½Π°Π»ΠΈΡΠΈΠΈ Π² Π°Π½Π°ΠΌΠ½Π΅Π·Π΅ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΠΏΠΎΡΠ΅ΠΊ ΠΈ Π±ΡΠΎΠ½Ρ
ΠΈΡΠ°, ΠΈ Π²ΡΡΠ΅ - ΠΏΡΠΈ ΡΠΎΠ²ΠΌΠ΅ΡΡΠ½ΠΎΠΌ ΠΏΡΠΈΠ΅ΠΌΠ΅ ΡΡΠ°ΡΠΈΠ½ΠΎΠ² ΠΈ Π³ΠΈΠΏΠΎΡΠ΅Π½Π·ΠΈΠ²Π½ΡΡ
ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠΎΠ², ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²Π΅Π½Π½ΠΎ. Π£ ΠΆΠ΅Π½ΡΠΈΠ½ ΡΠ°ΡΡΠΎΡΠ° ΡΠ΅ΡΠ΄Π΅ΡΠ½ΡΡ
ΡΠΎΠΊΡΠ°ΡΠ΅Π½ΠΈΠΉ >75 ΡΠ΄/ΠΌΠΈΠ½ ΠΈ ΡΡΠΌΠΌΠ°ΡΠ½Π°Ρ ΡΠΎΠ»ΡΠΈΠ½Π° ΠΊΠ°ΡΠΎΡΠΈΠ΄Π½ΡΡ
Π°ΡΠ΅ΡΠΎΡΠΊΠ»Π΅ΡΠΎΡΠΈΡΠ΅ΡΠΊΠΈΡ
Π±Π»ΡΡΠ΅ΠΊ Π°ΡΡΠΎΡΠΈΠΈΡΠΎΠ²Π°Π»ΠΈΡΡ Ρ Π±ΠΎΠ»Π΅Π΅ Π½ΠΈΠ·ΠΊΠΈΠΌΠΈ, Π° Π²ΠΈΠ·ΠΈΡ ΠΊ Π²ΡΠ°ΡΡ Π·Π° ΠΏΡΠΎΡΠ΅Π΄ΡΠΈΠΉ Π³ΠΎΠ΄ - Ρ Π±ΠΎΠ»Π΅Π΅ Π²ΡΡΠΎΠΊΠΈΠΌΠΈ ΡΠ°Π½ΡΠ°ΠΌΠΈ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΡΡΠΎΠ»Ρ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ.Π¦Π΅Π»Ρ. ΠΠ½Π°Π»ΠΈΠ· ΡΠ°ΠΊΡΠΎΡΠΎΠ², Π°ΡΡΠΎΡΠΈΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
Ρ Π²Π΅ΡΠΎΡΡΠ½ΠΎΡΡΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΡΡΠΎΠ»Ρ Π°ΡΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ Π³ΠΈΠΏΠ΅ΡΡΠΎΠ½ΠΈΠΈ (ΠΠ) Π² Π³ΠΈΠΏΠ΅ΡΡΠ΅Π½Π·ΠΈΠ²Π½ΠΎΠΉ ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΈ.ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΠ±ΡΠ΅ΠΊΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ - ΠΌΡΠΆΡΠΈΠ½Ρ ΠΈ ΠΆΠ΅Π½ΡΠΈΠ½Ρ ΡΠ΅ΠΏΡΠ΅Π·Π΅Π½ΡΠ°ΡΠΈΠ²Π½ΠΎΠΉ Π²ΡΠ±ΠΎΡΠΊΠΈ Π½Π΅ΠΎΡΠ³Π°Π½ΠΈΠ·ΠΎΠ²Π°Π½Π½ΠΎΠΉ ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΈ 25-64 Π»Π΅Ρ, ΡΡΡΠ°Π΄Π°ΡΡΠΈΠ΅ ΠΠ ΠΈ ΠΏΠΎΠ»ΡΡΠ°ΡΡΠΈΠ΅ ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΡΡ ΡΠ΅ΡΠ°ΠΏΠΈΡ. ΠΡΠ΅ ΡΡΠ°ΡΡΠ½ΠΈΠΊΠΈ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΏΡΠΎΡΠ»ΠΈ ΡΡΠ°Π½Π΄Π°ΡΡΠΈΠ·ΠΎΠ²Π°Π½Π½ΡΠΉ ΠΊΠ°ΡΠ΄ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΠΊΡΠΈΠ½ΠΈΠ½Π³, Π²ΠΊΠ»ΡΡΠ°ΡΡΠΈΠΉ ΠΎΠΏΡΠΎΡ ΠΏΠΎ ΡΡΠ΄Ρ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎ-Π΄Π΅ΠΌΠΎΠ³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΡ
, ΠΏΡΠΈΡ
ΠΎΡΠΎΡΠΈΠ°Π»ΡΠ½ΡΡ
, ΠΏΠΎΠ²Π΅Π΄Π΅Π½ΡΠ΅ΡΠΊΠΈΡ
ΠΏΠ΅ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ
, Π°Π½Π°ΠΌΠ½Π΅Π· ΠΈ ΡΠ΅ΠΌΠ΅ΠΉΠ½ΡΠΉ Ρ
Π°ΡΠ°ΠΊΡΠ΅Ρ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ, Π½Π°Π»ΠΈΡΠΈΠ΅ ΡΡΠ°Π΄ΠΈΡΠΈΠΎΠ½Π½ΡΡ
ΠΈ ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠΈΡΠΊΠ° ΡΠ΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΡΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ, ΠΎΡΠ΅Π½ΠΊΡ ΠΊΠ°ΡΠ΅ΡΡΠ²Π° ΠΆΠΈΠ·Π½ΠΈ, Π°Π½ΡΡΠΎΠΏΠΎΠΌΠ΅ΡΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΈΠ·ΠΌΠ΅ΡΠ΅Π½ΠΈΡ, ΠΈΠ·ΠΌΠ΅ΡΠ΅Π½ΠΈΠ΅ Π°ΡΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π΄Π°Π²Π»Π΅Π½ΠΈΡ (ΠΠ), ΡΠΎΠ»ΡΠΈΠ½Ρ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ° Β«ΠΈΠ½ΡΠΈΠΌΠ° - ΠΌΠ΅Π΄ΠΈΠ°Β», Π½Π°Π»ΠΈΡΠΈΡ ΠΈ ΡΡΠΌΠΌΠ°ΡΠ½ΠΎΠΉ ΡΠΎΠ»ΡΠΈΠ½Ρ ΠΊΠ°ΡΠΎΡΠΈΠ΄Π½ΡΡ
Π°ΡΠ΅ΡΠΎΡΠΊΠ»Π΅ΡΠΎΡΠΈΡΠ΅ΡΠΊΠΈΡ
Π±Π»ΡΡΠ΅ΠΊ. Π Π°Π½Π°Π»ΠΈΠ· Π²ΠΎΡΠ»ΠΈ Π΄Π°Π½Π½ΡΠ΅ 480 ΡΠ΅ΡΠΏΠΎΠ½Π΄Π΅Π½ΡΠΎΠ². ΠΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½Ρ ΠΌΠ΅ΡΠΎΠ΄Ρ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΠΈΡΠ΅ΡΠΊΠΈΠΉ ΠΈ Π½Π΅ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΠ°ΡΠΈΡΡΠΈΠΊΠΈ. ΠΠ»Ρ Π°Π½Π°Π»ΠΈΠ·Π° Π²Π·Π°ΠΈΠΌΠΎΡΠ²ΡΠ·Π΅ΠΉ ΠΏΡΠΈΠΌΠ΅Π½ΡΠ»ΠΈ ΠΌΠ½ΠΎΠ³ΠΎΡΠ°ΠΊΡΠΎΡΠ½ΡΡ Π»ΠΎΠ³ΠΈΡΡΠΈΡΠ΅ΡΠΊΡΡ ΡΠ΅Π³ΡΠ΅ΡΡΠΈΡ. ΠΠ΅ΡΠΎΡΡΠ½ΠΎΡΡΡ ΠΎΡΠΈΠ±ΠΊΠΈ <5% ΡΡΠΈΡΠ°Π»ΠΈ ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈ Π·Π½Π°ΡΠΈΠΌΠΎΠΉ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π‘ΠΎΠ³Π»Π°ΡΠ½ΠΎ ΠΎΡΠ΅Π½ΠΊΠ°ΠΌ, ΠΏΠΎΠ»ΡΡΠ΅Π½Π½ΡΠΌ Ρ ΠΏΠΎΠΏΡΠ°Π²ΠΊΠΎΠΉ Π½Π° Π²ΠΎΠ·ΡΠ°ΡΡ, ΡΡΠΎΠ²Π΅Π½Ρ Π΄ΠΎΡΡΠ°ΡΠΊΠ°, Π½Π°Π»ΠΈΡΠΈΠ΅ ΡΠ΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΡΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΠΈ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΏΡΠΈΠ½ΠΈΠΌΠ°Π΅ΠΌΡΡ
Π³ΠΈΠΏΠΎΡΠ΅Π½Π·ΠΈΠ²Π½ΡΡ
ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠΎΠ², Ρ ΠΌΡΠΆΡΠΈΠ½ ΡΠ°Π½ΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΠ ΠΏΠΎΠ²ΡΡΠ°Π»ΠΈ ΠΏΡΠΈΠ΅ΠΌ ΡΡΠ°ΡΠΈΠ½ΠΎΠ² ΠΈ ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΡΠΉ ΠΎΡΠ²Π΅Ρ Π½Π° Π²ΠΎΠΏΡΠΎΡ ΠΎ Π±ΠΎΠ»ΠΈ ΠΈΠ»ΠΈ Π΄ΠΈΡΠΊΠΎΠΌΡΠΎΡΡΠ΅ ΠΏΠΎ ΡΠΊΠ°Π»Π΅ EQ5D; ΠΏΠΎΠ½ΠΈΠΆΠ°Π»ΠΈ ΡΠ°Π½ΡΡ Π²ΡΡΠ²Π»Π΅Π½ΠΈΡ ΡΠ΅Π»Π΅Π²ΡΡ
ΡΡΠΎΠ²Π½Π΅ΠΉ ΠΠ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠΎΠ² ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠΈΠ½Π΄ΡΠΎΠΌΠ° ΠΊΡΠΎΠΌΠ΅ ΠΠ ΠΏΠΎ ΠΊΡΠΈΡΠ΅ΡΠΈΡΠΌ IDF (0-4), Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ ΠΏΠΎΡΠ΅ΠΊ, ΠΏΠ΅ΡΠ΅Π½Π΅ΡΠ΅Π½Π½ΡΠΉ Π±ΡΠΎΠ½Ρ
ΠΈΡ, Π²ΠΎΠ·ΡΠ°ΡΡ. ΠΡΡΠΌΡΡ Π°ΡΡΠΎΡΠΈΠ°ΡΠΈΡ Ρ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡΡ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΠ Ρ ΠΆΠ΅Π½ΡΠΈΠ½ ΠΏΠΎΠΊΠ°Π·Π°Π» Π²ΠΈΠ·ΠΈΡ ΠΊ Π²ΡΠ°ΡΡ Π·Π° ΠΏΡΠΎΡΠ΅Π΄ΡΠΈΠΉ Π³ΠΎΠ΄, ΠΎΠ±ΡΠ°ΡΠ½ΡΡ - ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠΎΠ² ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠΈΠ½Π΄ΡΠΎΠΌΠ°, ΡΠ°ΡΡΠΎΡΠ° ΡΠ΅ΡΠ΄Π΅ΡΠ½ΡΡ
ΡΠΎΠΊΡΠ°ΡΠ΅Π½ΠΈΠΉ β₯75 ΡΠ΄/ΠΌΠΈΠ½ ΠΈ ΡΡΠΌΠΌΠ°ΡΠ½Π°Ρ Π²ΡΡΠΎΡΠ° ΠΊΠ°ΡΠΎΡΠΈΠ΄Π½ΡΡ
Π°ΡΠ΅ΡΠΎΡΠΊΠ»Π΅ΡΠΎΡΠΈΡΠ΅ΡΠΊΠΈΡ
Π±Π»ΡΡΠ΅ΠΊ.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ ΠΏΠΎΠ΄ΡΠ΅ΡΠΊΠΈΠ²Π°ΡΡ Π²Π°ΠΆΠ½ΡΠΉ Π²ΠΊΠ»Π°Π΄ Π² Π½Π΅ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΊΠΎΠ½ΡΡΠΎΠ»Ρ ΠΠ ΡΠ°ΠΊΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ², ΠΊΠ°ΠΊ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠΈΡΠΊΠ°, Π²ΠΎΠ·ΡΠ°ΡΡ, Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ ΠΏΠΎΡΠ΅ΠΊ, Π²ΡΡΠΎΠΊΠ°Ρ ΡΠ°ΡΡΠΎΡΠ° ΡΠ΅ΡΠ΄Π΅ΡΠ½ΡΡ
ΡΠΎΠΊΡΠ°ΡΠ΅Π½ΠΈΠΉ, ΠΏΠ΅ΡΠ΅Π½Π΅ΡΠ΅Π½Π½ΡΠΉ Π±ΡΠΎΠ½Ρ
ΠΈΡ, Π½Π΅ΠΏΠΎΡΠ΅ΡΠ΅Π½ΠΈΠ΅ Π²ΡΠ°ΡΠ° Π·Π° ΠΏΡΠΎΡΠ΅Π΄ΡΠΈΠΉ Π³ΠΎΠ΄, Π° ΡΠ°ΠΊΠΆΠ΅ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΡΡΡ ΠΊΠ°ΡΠΎΡΠΈΠ΄Π½ΠΎΠ³ΠΎ Π°ΡΠ΅ΡΠΎΡΠΊΠ»Π΅ΡΠΎΠ·Π°. ΠΠ° ΡΠΈΡΡΠ°ΡΠΈΡ ΠΌΠΎΠΆΠ΅Ρ ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΠΎ Π²Π»ΠΈΡΡΡ Π½Π°ΠΌΠ΅ΡΠ΅Π½Π½ΠΎΠ΅ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΠ΅ ΠΈΠ·Π±ΡΡΠΎΡΠ½ΠΎΠ³ΠΎ Π²Π΅ΡΠ°, ΠΏΡΠΈΠ΅ΠΌ ΡΡΠ°ΡΠΈΠ½ΠΎΠ² Π»ΠΈΡΠ°ΠΌΠΈ ΠΎΡΠ΅Π½Ρ Π²ΡΡΠΎΠΊΠΎΠ³ΠΎ ΠΈ Π²ΡΡΠΎΠΊΠΎΠ³ΠΎ ΡΠΈΡΠΊΠ°, Π° ΡΠ°ΠΊΠΆΠ΅ ΡΠ΅Π³ΡΠ»ΡΡΠ½ΠΎΠ΅ ΠΏΠΎΡΠ΅ΡΠ΅Π½ΠΈΠ΅ Π²ΡΠ°ΡΠ°. ΠΠ΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎ Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠ΅Π΅ ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΡΠ°ΠΊΡΠΎΡΠΎΠ², Π·Π°ΡΡΡΠ΄Π½ΡΡΡΠΈΡ
Π΄ΠΎΡΡΠΈΠΆΠ΅Π½ΠΈΠ΅ ΡΠ΅Π»Π΅Π²ΡΡ
ΡΡΠΎΠ²Π½Π΅ΠΉ ΠΠ, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ², Π½Π°ΡΠ΅Π»Π΅Π½Π½ΡΡ
Π½Π° ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΠΊΡ ΠΈ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ ΠΊΠΎΡΡΠ΅ΠΊΡΠΈΡ ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ°ΡΡΡΡΠΎΠΉΡΡΠ²
Prescribing frequency and adherence to statins in outpatients with type 2 diabetes mellitus and comorbid cardiovascular diseases
BACKGROUND: Due to the high rate of growth in the incidence and burden of cardiovascular complications, type 2 diabetes mellitus (T2DM) is a significant medical problem in the world. Even in the absence of cardiovascular disease (CVD), patients with T2DM are classified as high and very high risk. In addition to glycemic control, an extremely important aspect of managing this group of patients is prevention of cardiovascular complications. T2DM and hyperlipidemia determines the target group for statins. At the same time, little is known about the frequency of administration of this class of drugs among people with T2DM.AIM: To study prescribing frequency and adherence to statins in outpatients with T2DM and comorbid cardiovascular diseases.METHODS: 156 patients with type 2 diabetes (87.2% β women, average age β 65.2 years) were examined as part of an outpatient appointment with an endocrinologist at the city polyclinic ofTomsk. We used a standard questionnaire compiled on the basis of adapted international methods, including information on cardiac pathology, medications, income level, and Morisky-Green test. Anthropometric parameters, fasting plasma glucose, glycated hemoglobin, lipid spectrum parameters were measured. Methods of parametric and nonparametric statistics were used for comparisons.RESULTS: Statins were prescribed to 45.0% of the surveyed, and 47.0% of them were constantly taking statins. In 41 and 39% of cases, statins were prescribed by an endocrinologist and a cardiologist, respectively. Those taking statins were characterized by a more severe functional class of angina pectoris (p=0.03), a higher prior myocardial infarction rate (p=0.01). For other concomitant diseases, and also indicators of carbohydrate metabolism, differences between the groups were not revealed. One third of patients were adherent (3β4 points), 2/3 were not adherent to treatment (0β2 points), respectively. Patients with incomes between 1 and 2 cost of living took statins more often than the rest (p=0.021).CONCLUSION: An insufficient frequency of prescription and adherence to statin therapy in patients with T2DM was revealed. In most cases, statins were prescribed by an endocrinologist or cardiologist. Functional class of angina pectoris, prior myocardial infarction and moderate income were associated with more frequent use of statins. To increase the coverage of patients with T2DM with statin treatment, more attention needs to be paid to the issues of CVD prevention from both medical professionals and patients
Pedagogical communication as a condition for the realization of the child's right to harmonious development
Π ΡΡΠ°ΡΡΠ΅ ΠΎΡΡΠ°ΠΆΠ΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΡΠ΅ΠΎΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΎΡΠΌΡΡΠ»Π΅Π½ΠΈΡ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ ΠΎΠΏΡΠΈΠΌΠΈΠ·Π°ΡΠΈΠΈ ΠΏΡΠΎΡΠ΅ΡΡΠ° ΠΎΠ±ΡΠ΅Π½ΠΈΡ ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΎΠ² Ρ Π΄Π΅ΡΡΠΌΠΈ Π² ΡΡΠ»ΠΎΠ²ΠΈΡΡ
Π΄ΠΎΡΠΊΠΎΠ»ΡΠ½ΠΎΠΉ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΠΉ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ.The article reflects the results of a theoretical understanding of the problem of optimizing the process of communication between teachers and children in a preschool educational organization
- β¦